Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025274 | 0.82 | SLC6A2 (0.36) | ALDH1A1HPGDALOX5TSHRSLC6A2 | |
| SCHEMBL9025551 | 0.79 | KDM4E (0.43) | LPAR1ALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL9026972 | 0.77 | LPAR1 (0.35) | LPAR1ALDH1A1HPGDSLC9A1TSHR | |
| SCHEMBL9026692 | 0.76 | ADORA3 (0.44) | LPAR1ALDH1A1HPGDSLC6A2SLC6A4 | |
| SCHEMBL9025673 | 0.76 | KMT2A (0.39) | ALDH1A1HPGDSLC9A1ALOX5NPC1 | |
| SCHEMBL9025095 | 0.73 | MAPT (0.38) | ALDH1A1HPGDTSHRNPC1RAB9A | |
| SCHEMBL9026477 | 0.73 | SLC9A1 (0.36) | ALDH1A1HPGDSLC9A1ALOX5GAA | |
| SCHEMBL9025806 | 0.72 | MAPT (0.39) | LPAR1ALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL9027093 | 0.72 | LMNA (0.36) | LPAR1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL84489 | 0.72 | LPAR1 (0.50) | LPAR1ALDH1A1HPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |