Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026692 | 0.89 | ADORA3 (0.44) | LMNARECQLS1PR4S1PR2S1PR3 | |
| SCHEMBL9025756 | 0.85 | NPC1 (0.44) | KMT2AALDH1A1RXFP1HPGDMEN1 | |
| SCHEMBL9025551 | 0.82 | KDM4E (0.43) | LMNAKMT2AALDH1A1LPAR1RXFP1 | |
| SCHEMBL9024526 | 0.81 | ALDH1A1 (0.33) | LMNARECQLS1PR3KMT2AALDH1A1 | |
| SCHEMBL9025806 | 0.80 | MAPT (0.39) | LMNAKMT2AALDH1A1LPAR1RXFP1 | |
| SCHEMBL9027103 | 0.76 | ACHE (0.35) | ACHES1PR4S1PR2S1PR3KMT2A | |
| SCHEMBL9025274 | 0.75 | SLC6A2 (0.36) | ACHES1PR3KMT2AALDH1A1HPGD | |
| SCHEMBL9025673 | 0.74 | KMT2A (0.39) | KMT2AALDH1A1HPGDCA1CA2 | |
| SCHEMBL9025817 | 0.72 | LPAR1 (0.36) | LMNAACHEKMT2AALDH1A1LPAR1 | |
| SCHEMBL9026962 | 0.72 | LPAR1 (0.37) | S1PR3ALDH1A1LPAR1HPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |