Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027103 | 0.89 | ACHE (0.35) | SLC6A2SLC6A4CHRM2CHRM1RRM1 | |
| SCHEMBL9025767 | 0.84 | SLC9A1 (0.37) | ALDH1A1POLBCTSAL3MBTL1MEN1 | |
| SCHEMBL9025568 | 0.82 | METAP2 (0.39) | SLC6A2SLC6A4LPAR1ALDH1A1POLB | |
| SCHEMBL9024534 | 0.81 | POLB (0.32) | SLC6A2SLC6A4ALDH1A1CRHR1POLB | |
| SCHEMBL9026972 | 0.77 | LPAR1 (0.35) | SLC6A2SLC6A4LPAR1ALDH1A1POLB | |
| SCHEMBL9025817 | 0.77 | LPAR1 (0.36) | SLC6A2SLC6A4LPAR1ALDH1A1CRHR1 | |
| SCHEMBL9026692 | 0.76 | ADORA3 (0.44) | SLC6A2SLC6A4CHRM2CHRM1RRM1 | |
| SCHEMBL9025682 | 0.74 | HTR2C (0.36) | POLBCTSAL3MBTL1MEN1KMT2A | |
| SCHEMBL9025107 | 0.72 | OPRK1 (0.35) | ALDH1A1SCN4APOLBL3MBTL1MEN1 | |
| SCHEMBL9025520 | 0.71 | METAP2 (0.38) | LPAR1ALDH1A1POLBACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |