Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634093 | 0.82 | BRD4 (0.43) | CES2IDO1TDO2 | |
| SCHEMBL9025658 | 0.81 | IDO1 (0.38) | IDO1TDO2ACP3 | |
| SCHEMBL30460663 | 0.81 | PNMT (0.47) | KMT2APNMTALDH1A1L3MBTL1KCNN4 | |
| SCHEMBL8632333 | 0.80 | ADRB1 (0.41) | — | |
| SCHEMBL8630297 | 0.80 | PFKFB3 (0.38) | ALDH1A1 | |
| SCHEMBL8631276 | 0.79 | BRD4 (0.41) | KMT2AIDO1TDO2ACP3KCNA5 | |
| SCHEMBL2593085 | 0.78 | SLC6A3 (0.44) | ALDH1A1IDO1TDO2SMN1; SMN2 | |
| SCHEMBL8631320 | 0.77 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8656491 | 0.77 | TP53 (0.40) | — | |
| SCHEMBL8629437 | 0.77 | BRD4 (0.45) | KMT2AL3MBTL1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707574-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | Astra Aktiebolag (SE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001968-A1 | NOVEL (1-PHENYL-1-HETEROCYCLYL)METHANOL AND (1-PHENYL-1-HETEROCYCLYL)METHYLAMINE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1995-01-19 | — | — | WO | disclosed |