SCHEMBL9027285

SCHEMBL9027285

CN(C(=O)NN)c1ccccc1Oc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSPO P30536 4/20 0.69
CTNNB1 P35222 1/20 0.46
ADRA2C P18825 1/20 0.43
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
POLB P06746 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 1/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11869356 0.74 TSPO (0.62) TSPOCTNNB1SLC6A2SLC6A4L3MBTL1
SCHEMBL1340529 0.74 TSPO (0.54) TSPORAB9ALMNA
SCHEMBL12722766 0.73 TSPO (0.62) TSPOCTNNB1SLC6A2SLC6A4LMNA
SCHEMBL27753964 0.73 TSPO (0.61) TSPOCTNNB1SLC6A2SLC6A4POLB
SCHEMBL9018864 0.72 PKM (0.53) POLBL3MBTL1RAB9ALMNAMEN1
SCHEMBL10221050 0.71 TSPO (0.55) TSPOADRA2CPOLBRAB9AKDM4E
SCHEMBL3650651 0.70 MEN1 (0.69) CTNNB1ADRA2CL3MBTL1RAB9AMEN1
Diphenylether SCHEMBL3677041 0.69 LTA4H (0.57) CTNNB1RAB9AKDM4E
SCHEMBL14839940 0.69 TSPO (0.56) TSPOCTNNB1SLC6A2SLC6A4L3MBTL1
SCHEMBL12700574 0.69 TSPO (0.57) TSPOCTNNB1SLC6A2SLC6A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996036615-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-11-21 WO disclosed
EP-0729461-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-04 EP disclosed