SCHEMBL3650651

SCHEMBL3650651

NNC(=O)c1ccccc1Oc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.69
KMT2A Q03164 4/20 0.69
CTNNB1 P35222 1/20 0.66
CTSD P07339 1/20 0.64
L3MBTL1 Q9Y468 3/20 0.61
NPSR1 Q6W5P4 1/20 0.61
ALDH1A1 P00352 4/20 0.60
RAB9A P51151 1/20 0.59
GAA P10253 2/20 0.58
MAPK8 P45983 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
HPGD P15428 1/20 0.58
HTT P42858 1/20 0.58
ATM Q13315 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MAPK1 P28482 2/20 0.55
HSD17B10 Q99714 1/20 0.55
KDM4E B2RXH2 1/20 0.55
TSHR P16473 1/20 0.52
ADRA2C P18825 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6329484 0.89 CTSD (0.72) MEN1KMT2ACTNNB1CTSDL3MBTL1
SCHEMBL7596694 0.87 MEN1 (0.57) MEN1KMT2ACTNNB1CTSDL3MBTL1
SCHEMBL974852 0.84 CTNNB1 (0.62) MEN1KMT2ACTNNB1L3MBTL1NPSR1
SCHEMBL22441045 0.82 MEN1 (0.52) MEN1KMT2ACTNNB1CTSDL3MBTL1
SCHEMBL5217469 0.82 ALDH1A1 (0.50) MEN1KMT2ACTNNB1CTSDL3MBTL1
SCHEMBL27674044 0.82 CTNNB1 (0.61) MEN1KMT2ACTNNB1L3MBTL1NPSR1
SCHEMBL6846935 0.82 RAB9A (0.63) MEN1KMT2ACTNNB1L3MBTL1NPSR1
SCHEMBL13883723 0.81 L3MBTL1 (0.62) MEN1KMT2ACTNNB1L3MBTL1NPSR1
SCHEMBL4180616 0.81 L3MBTL1 (0.65) MEN1KMT2ACTNNB1L3MBTL1NPSR1
SCHEMBL22319401 0.80 L3MBTL1 (0.82) KMT2AL3MBTL1NPSR1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250319056-A1 METHODS FOR TREATING CANCER UNIV INDIANA TRUSTEES (US) 2025-10-16 US disclosed
EP-4144792-B1 PARTICULATE WATER-ABSORBENT RESIN COMPOSITION, ABSORBENT BODY AND ABSORBENT ARTICLE SUMITOMO SEIKA CHEMICALS (JP) 2025-01-08 EP disclosed
EP-4144803-B1 WATER ABSORBENT RESIN COMPOSITION, ABSORBENT, AND ABSORBENT ARTICLE SUMITOMO SEIKA CHEMICALS (JP) 2024-12-25 EP disclosed
CN-115516043-B Particulate water-absorbent resin composition, absorber, and absorbent article 住友精化株式会社 2024-06-28 CN disclosed
CN-115443312-B Water-absorbent resin composition, absorber, and absorbent article 住友精化株式会社 2024-05-14 CN disclosed
US-20230182112-A1 PARTICULATE WATER-ABSORBING RESIN COMPOSITION, PRODUCTION METHOD THEREFOR, ABSORBENT OBJECT, AND ABSORBENT ARTICLE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2023-06-15 US disclosed
US-20230165999-A1 ABSORBENT ARTICLE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2023-06-01 US disclosed
US-20230166238-A1 PARTICULATE WATER-ABSORBENT RESIN COMPOSITION, ABSORBENT BODY AND ABSORBENT ARTICLE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2023-06-01 US disclosed
US-20230166237-A1 WATER ABSORBENT RESIN COMPOSITION, ABSORBENT, AND ABSORBENT ARTICLE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2023-06-01 US disclosed
EP-4144790-A1 PARTICULATE WATER-ABSORBING RESIN COMPOSITION, PRODUCTION METHOD THEREFOR, ABSORBENT OBJECT, AND ABSORBENT ARTICLE Sumitomo Seika Chemicals Co., Ltd. (JP) 2023-03-08 EP disclosed
EP-1392219-A2 SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOTOSIS AND THE USE THEREOF Cytovia, Inc. (US) 2004-03-03 EP disclosed
US-20030149110-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases HU LAIN-YEN (US) 2003-08-07 US disclosed
WO-2003045902-A1 BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES WARNER-LAMBERT COMPANY LLC (US) 2003-06-05 WO disclosed
EP-1314723-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases WARNER-LAMBERT COMPANY (US) 2003-05-28 EP disclosed
US-20030013743-A1 Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-01-16 US disclosed
WO-2002089745-A2 SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-11-14 WO disclosed
US-5023334-A Anthelmintic pyridinyl acylhydrazones THE UPJOHN COMPANY (US) 1991-06-11 US disclosed
US-5011932-A Anthelmintic pyridinyl acylhydrazones derivatives UPJOHN COMPANY (US) 1991-04-30 US disclosed
EP-0214158-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1987-03-18 EP disclosed
WO-1986004582-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1986-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149110-A1 Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases BCAT1, BCAT2, ABAT MEN1 2643/4885KMT2A 646/4885CTNNB1 951/4885
US-20250319056-A1 METHODS FOR TREATING CANCER HSP90AB1, HSP90B1, HSP90AB2P MEN1 3973/4885KMT2A 3452/4885CTNNB1 3412/4885
US-20030013743-A1 Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CASP2, CASP1, BCL2 MEN1 2707/4885KMT2A 2862/4885CTNNB1 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.