Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PLG | P00747 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGAV | P06756 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027764 | 1.00 | MMP2 (0.34) | MMP2ANPEPSIGMAR1CYP19A1F10 | |
| SCHEMBL9026520 | 0.89 | MMP2 (0.35) | MMP2ANPEPSIGMAR1CYP19A1F10 | |
| SCHEMBL9027149 | 0.88 | MMP2 (0.33) | MMP2ANPEPSIGMAR1 | |
| SCHEMBL9027157 | 0.88 | MMP2 (0.33) | MMP2ANPEPSIGMAR1 | |
| SCHEMBL9027929 | 0.87 | POLB (0.36) | SIGMAR1CYP19A1 | |
| SCHEMBL9037600 | 0.84 | VHL (0.32) | SIGMAR1CYP19A1 | |
| SCHEMBL9037597 | 0.84 | VHL (0.32) | SIGMAR1CYP19A1 | |
| SCHEMBL8833776 | 0.82 | SIGMAR1 (0.33) | MMP2ANPEPSIGMAR1CYP19A1 | |
| SCHEMBL9220068 | 0.82 | SIGMAR1 (0.33) | MMP2ANPEPSIGMAR1CYP19A1 | |
| SCHEMBL9026873 | 0.82 | SIGMAR1 (0.33) | SIGMAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |