Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 3/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026867 | 1.00 | SIGMAR1 (0.33) | SIGMAR1CYP19A1FAAHMGLLCHRM3 | |
| SCHEMBL9037597 | 0.86 | VHL (0.32) | SIGMAR1CYP19A1 | |
| SCHEMBL9037600 | 0.86 | VHL (0.32) | SIGMAR1CYP19A1 | |
| SCHEMBL9027929 | 0.85 | POLB (0.36) | SIGMAR1CYP19A1FAAHMGLL | |
| SCHEMBL9027764 | 0.82 | MMP2 (0.34) | SIGMAR1CYP19A1 | |
| SCHEMBL9027754 | 0.82 | MMP2 (0.34) | SIGMAR1CYP19A1 | |
| SCHEMBL9027724 | 0.77 | ECE1 (0.37) | SIGMAR1CYP19A1FAAHMGLLCHRM3 | |
| SCHEMBL9027814 | 0.77 | OPRM1 (0.31) | SIGMAR1 | |
| SCHEMBL9027810 | 0.77 | OPRM1 (0.31) | SIGMAR1 | |
| SCHEMBL9027719 | 0.77 | ECE1 (0.37) | SIGMAR1CYP19A1FAAHMGLLCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |