Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028355 | 0.87 | MAPT (0.41) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL9401168 | 0.83 | GAA (0.44) | MEN1KMT2ALMNAHTTNPSR1 | |
| SCHEMBL9401109 | 0.80 | ALDH1A1 (0.39) | MEN1KMT2ANPC1RAB9AMAOB | |
| SCHEMBL9029108 | 0.73 | TAS2R14 (0.39) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL9028921 | 0.73 | TAS2R14 (0.39) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL9027887 | 0.70 | MAPT (0.40) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL9550387 | 0.69 | L3MBTL1 (0.36) | MAPTMEN1KMT2ALMNANOTUM | |
| SCHEMBL9401106 | 0.69 | ALDH1A1 (0.58) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL9028773 | 0.68 | SCN10A (0.47) | MAPTLMNAXBP1 | |
| SCHEMBL9401101 | 0.68 | MAPT (0.44) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544587-B1 | Alpha-methylene-2-vinyl-benzeneacetic acid derivatives, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-05-29 | — | — | EP | claimed |