Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028343 | 0.81 | AKR1C3 (0.36) | RAB9AALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL30063431 | 0.79 | ALDH1A1 (0.50) | RAB9AALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL20640269 | 0.79 | LMNA (0.43) | RAB9AALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL5111143 | 0.79 | RAB9A (0.34) | RAB9AALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL15808531 | 0.79 | CPN1 (0.40) | RAB9AALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL8418308 | 0.79 | BLM (0.43) | RAB9AALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL12424223 | 0.76 | L3MBTL1 (0.47) | ALDH1A1KDM4ELMNAHSD17B10ATM | |
| SCHEMBL16659918 | 0.76 | RAB9A (0.36) | RAB9AALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL12351548 | 0.76 | SIGMAR1 (0.41) | ALDH1A1KDM4ELMNAHSD17B10ATM | |
| SCHEMBL15810913 | 0.75 | RAB9A (0.38) | RAB9AALDH1A1KDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716077-A1 | Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |