SCHEMBL397628

SCHEMBL397628

C=C(Cc1ccc(NS(C)(=O)=O)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.56
KDM4E B2RXH2 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
HTT P42858 1/20 0.56
KEAP1 Q14145 1/20 0.47
RECQL P46063 1/20 0.45
EPHX2 P34913 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
NPC1 O15118 1/20 0.44
AR P10275 1/20 0.44
RAB9A P51151 1/20 0.44
NR3C2 P08235 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
PGR P06401 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL398078 0.86 HPGD (0.57) HPGDSMN1; SMN2ALDH1A1LMNAHTT
SCHEMBL1422207 0.83 ALDH1A1 (0.63) HPGDKDM4ESMN1; SMN2ALDH1A1LMNA
SCHEMBL398666 0.82 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1KEAP1
SCHEMBL9028983 0.81 HPGD (0.61) HPGDKDM4ESMN1; SMN2ALDH1A1LMNA
SCHEMBL397676 0.80 HDAC1 (0.68) ALDH1A1LMNAKEAP1AR
SCHEMBL397357 0.80 ALDH1A1 (0.64) HPGDSMN1; SMN2ALDH1A1LMNARECQL
SCHEMBL11195052 0.80 HPGD (0.63) HPGDKDM4ESMN1; SMN2ALDH1A1LMNA
SCHEMBL5422613 0.79 HPGD (0.51) HPGDKDM4ESMN1; SMN2ALDH1A1LMNA
SCHEMBL6560601 0.79 HPGD (0.58) HPGDKDM4ESMN1; SMN2ALDH1A1LMNA
SCHEMBL3426193 0.78 CA2 (0.46) HPGDALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
EP-1972440-B1 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM CORP (JP) 2010-06-23 EP disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed