Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764099 | 0.84 | CA1 (0.36) | ALDH1A1MAPTKDM4EUSP2 | |
| SCHEMBL6768799 | 0.81 | SMN1; SMN2 (0.34) | ALDH1A1MAPTKDM4E | |
| SCHEMBL6130778 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4E | |
| SCHEMBL9028187 | 0.75 | CA1 (0.36) | ALDH1A1MAPTKDM4E | |
| SCHEMBL9028997 | 0.73 | LDHA (0.35) | ALDH1A1MAPTKDM4ELDHALDHB | |
| SCHEMBL9542181 | 0.71 | PTGS1 (0.38) | MAPTUSP2 | |
| SCHEMBL8633979 | 0.71 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4E | |
| SCHEMBL9028394 | 0.70 | MAOB (0.46) | ALDH1A1MAPTKDM4E | |
| SCHEMBL6767062 | 0.69 | CA1 (0.33) | ALDH1A1MAPTKDM4E | |
| SCHEMBL14113160 | 0.68 | MAPT (0.42) | ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445827-B1 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO KK (JP) | 1996-09-25 | — | — | EP | disclosed |