Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | LDHB | P07195 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130778 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL9028190 | 0.77 | MAOA (0.36) | ALDH1A1KDM4EMAPTMAOATRPV1 | |
| SCHEMBL9028403 | 0.73 | MAOB (0.46) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL9028993 | 0.73 | ALDH1A1 (0.35) | LDHALDHBALDH1A1KDM4EMAPT | |
| SCHEMBL9618439 | 0.72 | DHFR (0.34) | — | |
| SCHEMBL7022862 | 0.70 | KDM4E (0.34) | LDHALDHBALDH1A1KDM4EMAPT | |
| SCHEMBL8633979 | 0.69 | ALDH1A1 (0.34) | ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL8713373 | 0.67 | ALDH1A1 (0.31) | ALDH1A1KDM4EMAPT | |
| SCHEMBL14113160 | 0.66 | MAPT (0.42) | ALDH1A1KDM4EMAPTMTNR1AMTNR1B | |
| SCHEMBL30440069 | 0.66 | CTSB (0.39) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445827-B1 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO KK (JP) | 1996-09-25 | — | — | EP | disclosed |