Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18352336 | 0.87 | ALDH1A1 (0.43) | ALDH1A1HTTTDP1CYP1A2SCN5A | |
| SCHEMBL13248529 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HTTTDP1CYP1A2SCN5A | |
| SCHEMBL13248528 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HTTTDP1CYP1A2SCN5A | |
| SCHEMBL12911394 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HTTTDP1CYP1A2SCN5A | |
| SCHEMBL13248521 | 0.77 | SMN1; SMN2 (0.49) | ALDH1A1HTTTDP1CYP1A2MAPT | |
| SCHEMBL12909169 | 0.76 | CYP1A2 (0.68) | ALDH1A1HTTTDP1CYP1A2SCN5A | |
| SCHEMBL13248522 | 0.75 | POLB (0.44) | ALDH1A1HTTMAPTHPGDKDM4E | |
| SCHEMBL750158 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HTTTDP1CYP1A2SCN5A | |
| SCHEMBL939060 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HTTTDP1CYP1A2SCN5A | |
| SCHEMBL2362190 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HTTTDP1CYP1A2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041524-A1 | HYDRAZONOPYRAZOLONES AS PROTEIN TYROSINE PHOSPHATASE INHIBITORS | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (MDC) (DE) | 2012-04-05 | — | — | WO | disclosed |
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK SHARP & DOHME CORP. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | ALOX5, ALOX15, ALOX15B | ALDH1A1 159/4885HTT 4468/4885TDP1 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.