Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28854014 | 0.82 | CYP3A4 (0.49) | TDP1ALDH1A1CYP1A2HTTKMT2A | |
| SCHEMBL863443 | 0.79 | HTT (0.57) | TDP1ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL11317000 | 0.79 | HTT (0.49) | TDP1ALDH1A1CYP1A2HTTKMT2A | |
| SCHEMBL863399 | 0.78 | MEN1 (0.48) | TDP1ALDH1A1CYP1A2HTTKMT2A | |
| SCHEMBL4658055 | 0.78 | CYP3A4 (0.47) | TDP1ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL12527468 | 0.77 | ALDH1A1 (0.49) | TDP1ALDH1A1CYP1A2HTTKMT2A | |
| SCHEMBL863466 | 0.75 | GPR35 (0.51) | TDP1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6405854 | 0.74 | ALDH1A1 (0.50) | TDP1ALDH1A1CYP1A2HTTKMT2A | |
| SCHEMBL1321074 | 0.74 | MAPT (0.54) | TDP1ALDH1A1CYP1A2HTTKMT2A | |
| SCHEMBL13723969 | 0.74 | TDP1 (0.49) | TDP1ALDH1A1CYP1A2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621885-B1 | METHODS OF SYNTHESIZING 2-METHOXYMETHYL-1,4-BENZENEDIAMINE | PROCTER & GAMBLE (US) | 2014-10-29 | — | — | EP | disclosed |
| WO-2012044758-A1 | METHODS OF SYNTHESIZING 2-METHOXYMETHYL-1,4-BENZENEDIAMINE | THE PROCTER & GAMBLE COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |