Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641504 | 0.86 | TDP1 (0.53) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL792497 | 0.83 | ALDH1A1 (0.56) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11317000 | 0.83 | HTT (0.49) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL460989 | 0.82 | HTT (0.66) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL791991 | 0.81 | HTT (0.44) | HTTTDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL863170 | 0.81 | HSD17B10 (0.55) | HTTTDP1ALDH1A1CYP3A4GAA | |
| SCHEMBL18216619 | 0.81 | TDP1 (0.58) | HTTTDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL863466 | 0.81 | GPR35 (0.51) | TDP1ALDH1A1TSHRGAATHRB | |
| SCHEMBL2474262 | 0.81 | ALDH1A1 (0.51) | HTTTDP1ALDH1A1TSHRGAA | |
| SCHEMBL29625924 | 0.81 | ALDH1A1 (0.51) | HTTTDP1ALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309185-B2 | Process for preparing primary intermediates for dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2016-04-12 | — | — | US | claimed |
| US-9012691-B2 | Process for preparing primary intermediates for dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2015-04-21 | — | — | US | claimed |
| US-20140121414-A1 | Process for Preparing Primary Intermediates for Dyeing Keratin Fibers | THE PROCTER & GAMBLE COMPANY (US) | 2014-05-01 | — | — | US | claimed |
| US-20140121415-A1 | Process for Preparing Primary Intermediates for Dyeing Keratin Fibers | THE PROCTER & GAMBLE COMPANY (US) | 2014-05-01 | — | — | US | claimed |
| EP-1103542-B1 | Process for the preparation of 1,4-diamino-2-methoxymethyl-benzene and its salts and the use of these compounds in dyeing compositions for keratinous fibres | WELLA AG (DE) | 2004-04-28 | — | — | EP | claimed |
| US-20030041392-A1 | Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same | Wella GmbH (DE) | 2003-03-06 | — | — | US | claimed |
| EP-1103542-A2 | Process for the preparation of 1,4-diamino-2-methoxymethyl-benzene and its salts and the use of these compounds in dyeing compositions for keratinous fibres | Wella Aktiengesellschaft (DE) | 2001-05-30 | — | — | EP | claimed |
| JP-2067527-A | — | — | None | — | — | JP | disclosed |
| JP-2247620-A | — | — | None | — | — | JP | disclosed |
| EP-2912008-B1 | PROCESS FOR PREPARING 2-METHOXYMETHYL-1,4-BENZENEDIAMINE AND SALTS THEREOF | NOXELL CORP (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-2621888-B1 | METHODS OF SYNTHESIZING 2- SUBSTITUTED-1,4-BENZENEDIAMINE | NOXELL CORP (US) | 2018-09-12 | — | — | EP | disclosed |
| WO-2017095677-A1 | PROCESS FOR THE PREPARATION OF 2-ALKOXYMETHYL-1, 4-BENZENEDIAMINES | THE PROCTER & GAMBLE COMPANY (US) | 2017-06-08 | — | — | WO | disclosed |
| WO-2017095677-A1 | PROCESS FOR THE PREPARATION OF 2-ALKOXYMETHYL-1, 4-BENZENEDIAMINES | THE PROCTER & GAMBLE COMPANY (US) | 2017-06-08 | — | — | WO | disclosed |
| US-20030041392-A1 | Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same | Wella GmbH (DE) | 2003-03-06 | — | — | US | disclosed |
| EP-1103542-A3 | Process for the preparation of 1,4-diamino-2-methoxymethyl-benzene and its salts and the use of these compounds in dyeing compositions for keratinous fibres | Wella Aktiengesellschaft (DE) | 2001-12-05 | — | — | EP | disclosed |
| JP-2001151739-A | METHOD FOR PRODUCING 1,4-DIAMINO-2-METHOXYMETHYL- BENZENE AND ITS SALT, AND USE OF THESE COMPOUNDS AS DYESTUFF FOR KERATINOUS FIBER | WELLA AG | 2001-06-05 | — | — | JP | disclosed |
| EP-1103542-A2 | Process for the preparation of 1,4-diamino-2-methoxymethyl-benzene and its salts and the use of these compounds in dyeing compositions for keratinous fibres | Wella Aktiengesellschaft (DE) | 2001-05-30 | — | — | EP | disclosed |
| EP-1103542-A2 | Process for the preparation of 1,4-diamino-2-methoxymethyl-benzene and its salts and the use of these compounds in dyeing compositions for keratinous fibres | Wella Aktiengesellschaft (DE) | 2001-05-30 | — | — | EP | disclosed |
| JP-H02247620-A | MOLECULAR CRYSTAL | MIYATA SEIZO | 1990-10-03 | — | — | JP | disclosed |
| JP-H0267527-A | ORGANIC NONLINEAR OPTICAL MATERIAL | MIYATA SEIZO | 1990-03-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030041392-A1 | Process for making 1,4-diamino-2-methoxymethylbenzene and salts thereof and compositions and methods for dyeing keratin fibers containing same | KRT18, SCNN1B, DDAH1 | HTT 2413/4885TDP1 1142/4885ALDH1A1 308/4885 |
| US-20140121414-A1 | Process for Preparing Primary Intermediates for Dyeing Keratin Fibers | KRT18, VIM, F12 | HTT 4312/4885TDP1 3382/4885ALDH1A1 306/4885 |
| US-20140121415-A1 | Process for Preparing Primary Intermediates for Dyeing Keratin Fibers | KRT18, VIM, F12 | HTT 4312/4885TDP1 3382/4885ALDH1A1 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.