Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960110 | 0.84 | ALOX5 (0.46) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9999712 | 0.83 | CYP3A4 (0.53) | ALOX5MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11067722 | 0.83 | CYP3A4 (0.59) | ALOX5MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1099548 | 0.82 | MEN1 (0.55) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31191372 | 0.82 | ALDH1A1 (0.53) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13879003 | 0.81 | HTT (0.58) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL5838889 | 0.81 | KDM4E (0.50) | KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL1719601 | 0.81 | SMN1; SMN2 (0.68) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL419102 | 0.81 | ALOX5 (0.55) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16396603 | 0.81 | ALDH1A1 (0.51) | ALOX5MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485984-B1 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5225559-A | DIARYLMETHOXYPIPERIDINE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0485984-A2 | Diarylmethoxypiperidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |