Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034427 | 0.93 | OPRM1 (0.57) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9034357 | 0.89 | DRD2 (0.60) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9033141 | 0.86 | HTR2A (0.47) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9034241 | 0.86 | HTR7 (0.45) | KDM4EMAPTRAB9AHTR7HTR2A | |
| SCHEMBL9034780 | 0.86 | HTR1A (0.56) | KDM4EALDH1A1LMNAHTR7HTR2A | |
| SCHEMBL9034948 | 0.86 | KCNH2 (0.52) | KDM4EHTR7HTR2AOPRM1OPRL1 | |
| SCHEMBL9033694 | 0.85 | HTR1D (0.52) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9034861 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9034575 | 0.83 | MEN1 (0.48) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9033683 | 0.83 | SLC6A4 (0.64) | HTR7HTR2AOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |