SCHEMBL9033504

SCHEMBL9033504

CC=C(C(=O)O)c1sc2ccccc2c1CON=C(C)c1cccc(F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP5 Q96HI0 2/20 0.40
SENP2 Q9HC62 2/20 0.40
SENP1 Q9P0U3 2/20 0.40
PPARG P37231 5/20 0.38
PPARA Q07869 4/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
PKM P14618 1/20 0.35
MCL1 Q07820 4/20 0.35
BCL2 P10415 2/20 0.35
BCL2L1 Q07817 2/20 0.35
BAD Q92934 2/20 0.35
GAA P10253 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9032304 0.91 SENP5 (0.41) SENP5SENP2SENP1PPARGPPARA
SCHEMBL9033911 0.90 LMNA (0.42) PPARGPPARANPC1RAB9ALMNA
SCHEMBL9033740 0.89 MAOB (0.44) SENP5SENP2SENP1PPARGPPARA
SCHEMBL9032591 0.89 MAOA (0.44) SENP5SENP2SENP1PPARGPPARA
SCHEMBL9033070 0.88 LMNA (0.42) SENP5SENP2SENP1PPARGPPARA
SCHEMBL9032285 0.86 SENP5 (0.40) SENP5SENP2SENP1PPARGPPARA
SCHEMBL9032264 0.84 ALDH1A1 (0.39) SENP5SENP2SENP1PPARGPPARA
SCHEMBL9032865 0.83 NR1H4 (0.40) SENP5SENP2SENP1NPC1RAB9A
SCHEMBL9032132 0.81 HIF1A (0.44) SENP5SENP2SENP1PPARGPPARA
SCHEMBL9033686 0.81 HPGD (0.43) SENP5SENP2SENP1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621864-B1 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES CIBA GEIGY AG (CH) 1996-12-27 EP claimed