SCHEMBL9032865

SCHEMBL9032865

CC=C(C(=O)O)c1sc2ccccc2c1CON=C(C)c1cccc(OCC2CC2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 6/20 0.40
DGAT1 O75907 2/20 0.39
FABP1 P07148 1/20 0.36
GPR35 Q9HC97 1/20 0.35
BCL2 P10415 1/20 0.35
BCL2L1 Q07817 1/20 0.35
MCL1 Q07820 1/20 0.35
BAD Q92934 1/20 0.35
SENP5 Q96HI0 1/20 0.34
SENP2 Q9HC62 1/20 0.34
SENP1 Q9P0U3 1/20 0.34
S1PR1 P21453 1/20 0.34
HIF1A Q16665 1/20 0.34
MGLL Q99685 1/20 0.34
EDNRA P25101 1/20 0.33
MAOB P27338 1/20 0.33
KAT6A Q92794 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9032377 0.92 HIF1A (0.40) NR1H4DGAT1FABP1GPR35MCL1
SCHEMBL9032264 0.87 ALDH1A1 (0.39) BCL2BCL2L1MCL1BADSENP5
SCHEMBL9033911 0.84 LMNA (0.42) BCL2BCL2L1MCL1BADNPC1
SCHEMBL9032591 0.83 MAOA (0.44) BCL2BCL2L1MCL1BADSENP5
SCHEMBL9033504 0.83 SENP5 (0.40) BCL2BCL2L1MCL1BADSENP5
SCHEMBL9033740 0.83 MAOB (0.44) BCL2BCL2L1MCL1BADSENP5
SCHEMBL9033070 0.80 LMNA (0.42) SENP5SENP2SENP1NPC1RAB9A
SCHEMBL9033348 0.79 HIF1A (0.41) SENP5SENP2SENP1HIF1AMGLL
SCHEMBL9033686 0.76 HPGD (0.43) SENP5SENP2SENP1S1PR1NPC1
SCHEMBL9031467 0.74 MAOA (0.43) SENP5SENP2SENP1HIF1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0621864-B1 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES CIBA GEIGY AG (CH) 1996-12-27 EP claimed