Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.51 |
| ▸ | HTR1A | P08908 | 10/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | HTR7 | P34969 | 5/20 | 0.46 |
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032917 | 0.89 | SLC6A4 (0.65) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9033683 | 0.86 | SLC6A4 (0.64) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9035807 | 0.84 | CYP1A2 (0.54) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9034427 | 0.84 | OPRM1 (0.57) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9034449 | 0.82 | SLC6A4 (0.49) | SLC6A4HTR1ADRD2MEN1KMT2A | |
| SCHEMBL9034780 | 0.82 | HTR1A (0.56) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9051682 | 0.82 | KCNH2 (0.52) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9033765 | 0.82 | HTR1D (0.49) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9034948 | 0.82 | KCNH2 (0.52) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9034645 | 0.81 | RAD52 (0.51) | SLC6A4HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |