Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031742 | 0.81 | BDKRB1 (0.37) | ACHEBDKRB1MEN1KMT2A | |
| SCHEMBL9039532 | 0.77 | MYC (0.32) | LTB4R2BDKRB1 | |
| SCHEMBL9031434 | 0.74 | MYC (0.39) | ACHEBDKRB1PPARGMEN1KMT2A | |
| SCHEMBL9032114 | 0.71 | MYC (0.35) | BDKRB1MEN1KMT2A | |
| SCHEMBL9196004 | 0.69 | BDKRB1 (0.42) | LTB4R2BDKRB1 | |
| SCHEMBL8553594 | 0.68 | AGTR1 (0.44) | BDKRB1AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL3974805 | 0.64 | HPGD (0.37) | BDKRB1 | |
| SCHEMBL9199570 | 0.63 | ALDH1A1 (0.39) | AGTR1AGTR2MEN1KMT2A | |
| SCHEMBL9443122 | 0.62 | FNTA (0.37) | LTB4R2BDKRB1PPARGMEN1KMT2A | |
| SCHEMBL9197854 | 0.60 | ALDH1A1 (0.39) | AGTR1AGTR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483683-B1 | Thienoimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| EP-0483683-A2 | Thienoimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |