Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033801 | 0.93 | KCNH2 (0.39) | KCNH2EPHX2PPARGPPARAMC4R | |
| SCHEMBL9033715 | 0.89 | KMT2A (0.42) | PPARAF2P2RX7 | |
| SCHEMBL9033473 | 0.87 | ANPEP (0.47) | F2MC4RMMEALDH1A1 | |
| SCHEMBL9033723 | 0.82 | F2 (0.39) | F2P2RX7 | |
| SCHEMBL9033512 | 0.79 | POLB (0.46) | MC4R | |
| SCHEMBL9033478 | 0.79 | ANPEP (0.44) | MC4RALDH1A1 | |
| SCHEMBL9033533 | 0.77 | HPGD (0.31) | — | |
| SCHEMBL9032679 | 0.76 | L3MBTL1 (0.31) | MMEACECPA1ACE2 | |
| SCHEMBL9033517 | 0.75 | POLB (0.40) | — | |
| SCHEMBL2639584 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |