Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033715 | 0.93 | KMT2A (0.42) | F2P2RX7KMT2APSMB5MEN1 | |
| SCHEMBL9033801 | 0.89 | KCNH2 (0.39) | P2RX7 | |
| SCHEMBL9033478 | 0.86 | ANPEP (0.44) | KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL9033796 | 0.82 | KCNH2 (0.41) | F2P2RX7 | |
| SCHEMBL9033517 | 0.80 | POLB (0.40) | KMT2AMEN1 | |
| SCHEMBL9033473 | 0.78 | ANPEP (0.47) | F2KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL9033512 | 0.77 | POLB (0.46) | KMT2AMEN1 | |
| SCHEMBL9032688 | 0.73 | L3MBTL1 (0.33) | KMT2AMEN1 | |
| SCHEMBL9033881 | 0.72 | ALDH1A1 (0.43) | KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL9033847 | 0.71 | TACR1 (0.40) | KMT2APSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |