Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033517 | 0.92 | POLB (0.40) | POLBHTTKMT2AMEN1TSHR | |
| SCHEMBL9033473 | 0.92 | ANPEP (0.47) | KMT2AMEN1TSHRANPEPMC4R | |
| SCHEMBL9033478 | 0.88 | ANPEP (0.44) | KMT2AMEN1CTSLCTSBANPEP | |
| SCHEMBL9033870 | 0.86 | HTT (0.46) | POLBHTTKMT2AMEN1CYP2C9 | |
| SCHEMBL9032637 | 0.83 | MEN1 (0.46) | POLBKMT2AMEN1 | |
| SCHEMBL9033533 | 0.81 | HPGD (0.31) | HTT | |
| SCHEMBL9033715 | 0.80 | KMT2A (0.42) | KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL9032679 | 0.80 | L3MBTL1 (0.31) | — | |
| SCHEMBL9033796 | 0.79 | KCNH2 (0.41) | MC4R | |
| SCHEMBL9033881 | 0.79 | ALDH1A1 (0.43) | POLBHTTKMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |