Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033723 | 0.93 | F2 (0.39) | KMT2AF2P2RX7MEN1MLYCD | |
| SCHEMBL9033796 | 0.89 | KCNH2 (0.41) | F2P2RX7PPARA | |
| SCHEMBL9033473 | 0.86 | ANPEP (0.47) | KMT2AF2MEN1MASP2 | |
| SCHEMBL9033801 | 0.82 | KCNH2 (0.39) | P2RX7PPARA | |
| SCHEMBL9033512 | 0.80 | POLB (0.46) | KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL9033478 | 0.78 | ANPEP (0.44) | KMT2AMEN1MASP2 | |
| SCHEMBL9033517 | 0.77 | POLB (0.40) | KMT2AMEN1CYP2D6CYP2C19 | |
| SCHEMBL9033533 | 0.74 | HPGD (0.31) | — | |
| SCHEMBL9032679 | 0.73 | L3MBTL1 (0.31) | — | |
| SCHEMBL3882782 | 0.73 | MLYCD (0.56) | KMT2AP2RX7MEN1MLYCDPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |