SCHEMBL9033533

SCHEMBL9033533

CCC(C)[C@H](NCC1CC(S)CN1)C(=O)NCC(C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9033537 0.90 L3MBTL1 (0.32) HTT
SCHEMBL9032679 0.86 L3MBTL1 (0.31)
SCHEMBL9033802 0.82 ENPEP (0.33) HTT
SCHEMBL9033512 0.81 POLB (0.46) HTT
SCHEMBL9033814 0.81 LMNA (0.37) HPGD
SCHEMBL9033473 0.81 ANPEP (0.47)
SCHEMBL9032688 0.81 L3MBTL1 (0.33) HTT
SCHEMBL9033791 0.80
SCHEMBL9033796 0.77 KCNH2 (0.41)
SCHEMBL9033517 0.77 POLB (0.40) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696593-A2 Inhibitors of farnesyl protein transferase BRISTOL-MYERS SQUIBB COMPANY (US) 1996-02-14 EP disclosed