SCHEMBL9033802

SCHEMBL9033802

CCC(C)[C@H](NCC1CC(S)CN1)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9032679 0.85 L3MBTL1 (0.31) L3MBTL1
SCHEMBL9033533 0.82 HPGD (0.31) HTT
SCHEMBL9033791 0.81
SCHEMBL9032688 0.77 L3MBTL1 (0.33) L3MBTL1HTT
SCHEMBL9033537 0.77 L3MBTL1 (0.32) L3MBTL1HTT
SCHEMBL9034245 0.77 L3MBTL1 (0.35) ENPEPL3MBTL1HTT
SCHEMBL9033512 0.76 POLB (0.46) HTT
SCHEMBL9033473 0.76 ANPEP (0.47)
SCHEMBL9032637 0.76 MEN1 (0.46)
SCHEMBL9033807 0.76 DPP4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696593-A2 Inhibitors of farnesyl protein transferase BRISTOL-MYERS SQUIBB COMPANY (US) 1996-02-14 EP disclosed