SCHEMBL9033537

SCHEMBL9033537

CC[C@H](C)[C@H](NCC(C)C)C(=O)NCC1CC(S)CN1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9033533 0.90 HPGD (0.31) HTT
SCHEMBL9032688 0.86 L3MBTL1 (0.33) L3MBTL1HTT
SCHEMBL9033517 0.81 POLB (0.40) HTT
SCHEMBL9033822 0.81 ALDH1A1 (0.33) L3MBTL1
SCHEMBL9032679 0.81 L3MBTL1 (0.31) L3MBTL1
SCHEMBL9032567 0.81 GPR88 (0.32) L3MBTL1
SCHEMBL9033807 0.80 DPP4 (0.35)
SCHEMBL9033793 0.77
SCHEMBL9033802 0.77 ENPEP (0.33) L3MBTL1HTT
SCHEMBL9033473 0.77 ANPEP (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0696593-A2 Inhibitors of farnesyl protein transferase BRISTOL-MYERS SQUIBB COMPANY (US) 1996-02-14 EP disclosed