Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034005 | 0.85 | CTSL (0.43) | CTSLCTSBCTSKSYKOPRK1 | |
| SCHEMBL9033818 | 0.85 | CTSL (0.45) | CTSLCTSBCTSKSYKOPRK1 | |
| SCHEMBL9033091 | 0.84 | CTSL (0.46) | CTSLCTSBCTSKSYKOPRK1 | |
| SCHEMBL9032726 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL9032737 | 0.76 | CTSL (0.44) | CTSLCTSBCTSKOPRK1ITGB3 | |
| SCHEMBL9031818 | 0.76 | CTSL (0.44) | CTSLCTSBCTSKOPRK1ITGB3 | |
| SCHEMBL9033158 | 0.73 | OPRK1 (0.43) | CTSLCTSBCTSKOPRK1ITGB3 | |
| SCHEMBL9034307 | 0.73 | OPRK1 (0.48) | CTSLCTSKSYKOPRK1ITGB3 | |
| SCHEMBL9050704 | 0.72 | MEN1 (0.38) | OPRK1ITGB3ITGA2B | |
| SCHEMBL7286508 | 0.72 | CTSL (0.62) | CTSLCTSBCTSKSYKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |