Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032737 | 0.89 | CTSL (0.44) | CTSLCTSBCTSKSMN1; SMN2CYP3A4 | |
| SCHEMBL9031818 | 0.89 | CTSL (0.44) | CTSLCTSBCTSKSMN1; SMN2CYP3A4 | |
| SCHEMBL9033014 | 0.85 | POLB (0.42) | RAB9ACAPN1LMNAMEN1KMT2A | |
| SCHEMBL9033094 | 0.80 | ITGB3 (0.45) | CTSLCTSBCTSKSMN1; SMN2CYP3A4 | |
| SCHEMBL9033818 | 0.79 | CTSL (0.45) | CTSLCTSBCTSKSMN1; SMN2CYP3A4 | |
| SCHEMBL9033091 | 0.78 | CTSL (0.46) | CTSLCTSBCTSKSMN1; SMN2CYP3A4 | |
| SCHEMBL9034593 | 0.76 | CYP3A4 (0.39) | CTSLCTSBCTSKSMN1; SMN2CYP3A4 | |
| SCHEMBL8697846 | 0.76 | OPRK1 (0.44) | CTSLCTSBCTSKSMN1; SMN2CYP3A4 | |
| SCHEMBL9033877 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2D6CYP2C9ATMLMNA | |
| SCHEMBL9034272 | 0.75 | ATM (0.45) | CTSLCTSBCTSKSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |