SCHEMBL9035137

SCHEMBL9035137

N#Cc1c(Br)c(C(F)(F)F)n(CC(Oc2ccc(Cl)cc2)C(=O)O)c1-c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.43
PPARA Q07869 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9037286 0.79 MMP2 (0.38) PPARG
SCHEMBL9036109 0.79 TP53 (0.37) PPARGPPARA
SCHEMBL9035868 0.77 ALDH1A1 (0.38)
SCHEMBL7508068 0.77 KDM4E (0.37) PPARG
SCHEMBL7499361 0.77 KDM4E (0.37) PPARG
SCHEMBL9057679 0.76 HTT (0.36) PPARG
SCHEMBL31536512 0.76 POLB (0.35)
SCHEMBL8994487 0.75 POLB (0.36)
SCHEMBL5819212 0.75 KDM4E (0.34) PPARG
SCHEMBL7504784 0.75 MAPT (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594940-B1 N-oxy- and thioalkylcarbonyloxyalkypyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed
EP-0594940-A1 N-oxy- and thioalkylcarbonyloxyalkypyrrole insecticidal, acaricidal and molluscicidal agents AMERICAN CYANAMID COMPANY (US) 1994-05-04 EP claimed