Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034918 | 0.94 | TYMP (0.33) | — | |
| SCHEMBL9035977 | 0.72 | HRH3 (0.38) | — | |
| SCHEMBL18377716 | 0.65 | CYP2A13 (0.40) | — | |
| SCHEMBL9034922 | 0.64 | TYMP (0.41) | — | |
| SCHEMBL19589388 | 0.62 | ALOX15 (0.45) | — | |
| SCHEMBL1610726 | 0.61 | NCF1 (0.41) | — | |
| SCHEMBL16083430 | 0.60 | CYP1A2 (0.41) | OPRK1 | |
| SCHEMBL12715997 | 0.60 | CXCR4 (0.37) | — | |
| SCHEMBL7754819 | 0.59 | — | — | |
| SCHEMBL3437040 | 0.57 | ALDH1A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737192-A1 | SUBSTITUTED MORPHOLINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018124-A1 | SUBSTITUTED MORPHOLINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 1995-07-06 | — | — | WO | disclosed |