Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33921 | 0.92 | CYP2C19 (0.47) | CYP2C19ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL516400 | 0.89 | CYP2C19 (0.48) | CYP2C19ALDH1A1TDP1KDM4EEGFR | |
| SCHEMBL4358315 | 0.89 | EGFR (0.43) | CYP2C19ALDH1A1TDP1KDM4EEGFR | |
| Lithium Ion SCHEMBL19732659 | 0.87 | CYP2C19 (0.47) | CYP2C19ALDH1A1TDP1KDM4EEGFR | |
| SCHEMBL21065737 | 0.87 | CYP2C19 (0.47) | CYP2C19ALDH1A1TDP1KDM4EEGFR | |
| SCHEMBL2765786 | 0.86 | MAPT (0.49) | CYP2C19ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL17122222 | 0.84 | CYP2C19 (0.41) | CYP2C19ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL2489238 | 0.83 | CYP2C19 (0.44) | CYP2C19ALDH1A1TDP1EGFRERBB2 | |
| SCHEMBL2759055 | 0.82 | ALDH1A1 (0.43) | CYP2C19ALDH1A1TDP1EGFRERBB2 | |
| SCHEMBL19415813 | 0.82 | TDP1 (0.55) | CYP2C19ALDH1A1TDP1KDM4EEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170055-A1 | TARGETED CONTRAST AGENTS FOR MRI OF AMYLOID DEPOSITION | TEXAS CHILDREN'S HOSPITAL (US) | 2021-06-10 | — | — | US | disclosed |
| US-20180186734-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2018-07-05 | — | — | US | disclosed |
| US-9504753-B2 | Nanometer-sized prodrugs of NSAIDs | CEDARS-SINAI MEDICAL CENTER (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160194316-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. | 2016-07-07 | — | — | US | disclosed |
| US-20160152604-A1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | Epizyme, Inc. | 2016-06-02 | — | — | US | disclosed |
| US-9315494-B2 | Alkyl-amide-substituted pyridyl compounds useful as modulators of IL-12, IL-23 and/or IFNα responses | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-04-19 | — | — | US | disclosed |
| US-20160031907-A1 | Substituted Benzene Compounds | Epizyme, Inc. | 2016-02-04 | — | — | US | disclosed |
| US-20160024081-A1 | Substituted 6,5-Fused Bicyclic Heteroaryl Compounds | Epizyme, Inc. | 2016-01-28 | — | — | US | disclosed |
| US-9028874-B2 | Antioxidant nanosphere comprising [1,2]-dithiolane moieties | CEDARS-SINAI MEDICAL CENTER (US) | 2015-05-12 | — | — | US | disclosed |
| US-20140045815-A1 | INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/BETA-CATENIN SIGNALING PATHWAY INHIBITORS | SAMUMED, LLC (US) | 2014-02-13 | — | — | US | disclosed |
| WO-2012043890-A1 | GAP EMBEDDING COMPOSITION, METHOD OF EMBEDDING GAP AND METHOD OF PRODUCING SEMICONDUCTOR DEVICE BY USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2012-04-05 | — | — | WO | disclosed |
| US-20090278084-A1 | Cure accelerators for anaerobic curable compositions | HENKEL CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186734-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DDT, PTMS, TIAL1 | CYP2C19 445/4885ALDH1A1 2702/4885TDP1 1098/4885 |
| US-20210170055-A1 | TARGETED CONTRAST AGENTS FOR MRI OF AMYLOID DEPOSITION | PSEN1, APP, PHOSPHO1 | CYP2C19 4296/4885ALDH1A1 4251/4885TDP1 2570/4885 |
| US-20160024081-A1 | Substituted 6,5-Fused Bicyclic Heteroaryl Compounds | CYP3A5, PAICS, CYP4B1 | CYP2C19 29/4885ALDH1A1 594/4885TDP1 2062/4885 |
| US-20160031907-A1 | Substituted Benzene Compounds | CYP1B1, CYP4B1, CYP2B6 | CYP2C19 26/4885ALDH1A1 112/4885TDP1 2257/4885 |
| US-20140045815-A1 | INDAZOLE-3-CARBOXAMIDES AND THEIR USE AS WNT/BETA-CATENIN SIGNALING PATHWAY INHIBITORS | WNT3, WNT1, WNT3A | CYP2C19 2335/4885ALDH1A1 1364/4885TDP1 3534/4885 |
| US-20090278084-A1 | Cure accelerators for anaerobic curable compositions | EGLN3, INO80, IDH2 | CYP2C19 831/4885ALDH1A1 554/4885TDP1 1420/4885 |
| US-20160152604-A1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP3A5, PAICS | CYP2C19 48/4885ALDH1A1 552/4885TDP1 2000/4885 |
| US-20160194316-A1 | SUBSTITUTED BENZENE COMPOUNDS | CYP1B1, TP53, VHL | CYP2C19 140/4885ALDH1A1 358/4885TDP1 1398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.