Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.49 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040061 | 0.96 | SIGMAR1 (0.50) | SIGMAR1EBPOPRM1 | |
| SCHEMBL9040998 | 0.91 | SIGMAR1 (0.47) | SIGMAR1EBPOPRM1 | |
| SCHEMBL9040103 | 0.86 | SIGMAR1 (0.38) | SIGMAR1EBPOPRM1 | |
| SCHEMBL9040626 | 0.84 | DRD1 (0.47) | SIGMAR1 | |
| SCHEMBL9037928 | 0.80 | KDM1A (0.46) | SIGMAR1EBP | |
| SCHEMBL9845106 | 0.76 | SIGMAR1 (0.41) | SIGMAR1EBP | |
| SCHEMBL9040970 | 0.75 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL9040756 | 0.73 | DRD1 (0.48) | — | |
| SCHEMBL5573072 | 0.73 | OPRM1 (0.51) | SIGMAR1EBPOPRM1 | |
| SCHEMBL5569403 | 0.72 | OPRM1 (0.50) | SIGMAR1EBPOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441598-B1 | Spiroisoindole compounds | ZENECA INC (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5098925-A | Neurological disorders in mammals | ICI AMERICAS INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0441598-A2 | Spiroisoindole compounds | ZENECA INC. (US) | 1991-08-14 | — | — | EP | disclosed |