Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573077 | 0.81 | SIGMAR1 (0.41) | OPRM1SIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL5573072 | 0.80 | OPRM1 (0.51) | OPRM1SIGMAR1EBP | |
| SCHEMBL9037683 | 0.72 | SIGMAR1 (0.49) | OPRM1SIGMAR1EBP | |
| SCHEMBL9040998 | 0.71 | SIGMAR1 (0.47) | OPRM1SIGMAR1EBP | |
| SCHEMBL9040061 | 0.71 | SIGMAR1 (0.50) | OPRM1SIGMAR1EBP | |
| SCHEMBL5573856 | 0.70 | HTT (0.41) | OPRM1SIGMAR1EBP | |
| SCHEMBL5570577 | 0.68 | OPRM1 (0.38) | OPRM1SIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL4910329 | 0.66 | MDM2 (0.58) | ALDH1A1CYP2D6 | |
| SCHEMBL4910331 | 0.66 | MDM2 (0.58) | ALDH1A1CYP2D6 | |
| SCHEMBL4025928 | 0.65 | SIGMAR1 (0.45) | OPRM1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786773-A1 | ISOINDOLIN-1-ONE DERIVATIVES | Cancer Research Technology Limited (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006024837-A1 | ISOINDOLIN-1-ONE DERIVATIVES | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2006-03-09 | — | — | WO | disclosed |