Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931688 | 0.88 | COMT (0.51) | CA1CA2CA9MAPK1COMT | |
| SCHEMBL10480797 | 0.79 | CA1 (0.58) | CA1CA2CA9MAPK1HTT | |
| SCHEMBL9259006 | 0.76 | ALDH1A1 (0.60) | CA1CA2CA9MAPK1COMT | |
| SCHEMBL10567062 | 0.75 | CA2 (0.47) | CA1CA2CA9ADRA2CADRA1D | |
| SCHEMBL10834405 | 0.75 | COMT (0.51) | CA1CA2CA9MAPK1COMT | |
| SCHEMBL28206332 | 0.75 | COMT (0.49) | CA1CA2CA9MAPK1COMT | |
| SCHEMBL18940883 | 0.75 | KDM4E (0.44) | COMTADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL7416794 | 0.74 | LOXL2 (0.42) | COMTADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL9038070 | 0.73 | FTO (0.51) | CA1CA2CA9MAPK1TSHR | |
| SCHEMBL19211643 | 0.73 | CA2 (0.49) | CA1CA2CA9MAPK1COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273610-B1 | Herbicidal pyridinesulfonylureas | DU PONT (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5512535-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| US-5393733-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5209770-A | Containing pyrimidine ring | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5102444-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0334896-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |
| WO-1989001937-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-03-09 | — | — | WO | disclosed |
| US-4774337-A | Herbicidal pyridinesulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0273610-A1 | Herbicidal pyridinesulfonylureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| WO-1988004297-A1 | HERBICIDAL PYRIDINESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-16 | — | — | WO | disclosed |