Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464614 | 0.77 | MAPT (0.64) | MAOAMAOBACHEBCHEALDH1A1 | |
| SCHEMBL9039530 | 0.77 | MAPK14 (0.47) | MAOAMAOBACHEALDH1A1MAPT | |
| SCHEMBL12692736 | 0.73 | ALDH1A1 (0.57) | ACHEBCHEALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6152266 | 0.73 | L3MBTL1 (0.76) | MAOAALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL11835361 | 0.72 | CYP1A2 (0.69) | MAOAMAOBACHEBCHEALDH1A1 | |
| SCHEMBL9038911 | 0.72 | MAPK14 (0.47) | MAOAMAOBACHEALDH1A1MAPT | |
| SCHEMBL31277034 | 0.72 | MAPT (0.69) | ALDH1A1MAPTL3MBTL1KDM4EHPGD | |
| SCHEMBL24277130 | 0.71 | MAPT (0.55) | MAOAMAOBACHEBCHEALDH1A1 | |
| SCHEMBL24276984 | 0.70 | ACHE (0.55) | MAOAMAOBACHEBCHEALDH1A1 | |
| SCHEMBL29445058 | 0.70 | ACHE (0.55) | MAOAMAOBACHEBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347831-B1 | Pyridine derivatives and intermediates thereof | KYOWA HAKKO KOGYO KK (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-4971964-A | INHIBITORS OF THROMBOXANE SYNTHASE, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORU AGENTS, CANCER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0347831-A2 | Pyridine derivatives and intermediates thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |