Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GCG | P01275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039943 | 0.82 | CYP3A4 (0.40) | NPC1RAB9AL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL6988127 | 0.80 | RAB9A (0.68) | NPC1RAB9AL3MBTL1CYP2C9 | |
| SCHEMBL6993812 | 0.78 | NPC1 (0.47) | NPC1RAB9AMMEACELMNA | |
| SCHEMBL9037906 | 0.75 | NPC1 (0.48) | NPC1RAB9ALMNAL3MBTL1NPSR1 | |
| SCHEMBL1664507 | 0.73 | CYP1A2 (0.44) | NPC1RAB9AL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL9037774 | 0.73 | NPSR1 (0.47) | NPC1RAB9ALMNANPSR1ITGB3 | |
| SCHEMBL6992210 | 0.72 | CNR2 (0.64) | NPC1RAB9AMMEACE | |
| SCHEMBL26205734 | 0.69 | MAPK1 (0.43) | NPC1RAB9ALMNACA1CA2 | |
| SCHEMBL6796081 | 0.69 | LMNA (0.40) | LMNAL3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1520499 | 0.67 | L3MBTL1 (0.61) | NPC1RAB9ALMNAL3MBTL1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441349-B1 | Pyrroloazepine derivatives | SUNTORY LTD (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-5416082-A | Antiserotonine agents | SUNTORY LIMITED (JP) | 1995-05-16 | — | — | US | disclosed |
| US-5391731-A | Useful therapeutics for circulatory diseases | SUNTORY LIMITED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5206239-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0441349-A1 | Pyrroloazepine derivatives | SUNTORY LIMITED (JP) | 1991-08-14 | — | — | EP | disclosed |