Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | PDE6D | O43924 | 3/20 | 0.54 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.54 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041081 | 0.94 | ALDH1A1 (0.51) | TP53ALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL9042322 | 0.93 | KDM4E (0.66) | TP53ALDH1A1PDE6DHTTSMN1; SMN2 | |
| SCHEMBL9041371 | 0.91 | PDE6D (0.54) | TP53ALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL9042158 | 0.91 | GRM2 (0.53) | TP53ALDH1A1PDE6DALDH2ALDH3A1 | |
| SCHEMBL9040419 | 0.90 | HDAC1 (0.52) | HTTDRD2TBXA2RAGTR2HRH3 | |
| SCHEMBL9040202 | 0.89 | DRD2 (0.57) | TP53ALDH1A1PDE6DHTTSMN1; SMN2 | |
| SCHEMBL9042213 | 0.89 | PPARG (0.47) | ALDH1A1HTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL9039784 | 0.88 | PPARG (0.46) | ALDH1A1HTTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL9043424 | 0.88 | GRM2 (0.53) | ALDH1A1PDE6DHTTSMN1; SMN2KDM4E | |
| SCHEMBL9040956 | 0.88 | ALDH1A1 (0.61) | TP53ALDH1A1PDE6DALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |