Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17103072 | 0.95 | PRPS1 (0.53) | PRPS1LMNARAB9ANPC1PKM | |
| SCHEMBL11557672 | 0.87 | LMNA (0.60) | PRPS1LMNARAB9ANPC1PKM | |
| SCHEMBL9038637 | 0.87 | MAPT (0.57) | PRPS1LMNARAB9ANPC1PKM | |
| SCHEMBL259900 | 0.83 | PRPS1 (0.51) | PRPS1LMNARAB9ANPC1PKM | |
| SCHEMBL13668153 | 0.81 | PRPS1 (0.50) | PRPS1LMNARAB9ANPC1PKM | |
| SCHEMBL9040262 | 0.79 | PRPS1 (0.52) | PRPS1LMNARAB9ANPC1PKM | |
| SCHEMBL11331909 | 0.79 | NPC1 (0.52) | PRPS1LMNARAB9ANPC1PKM | |
| SCHEMBL9040429 | 0.78 | MTNR1A (0.61) | LMNARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL17103033 | 0.78 | BRD4 (0.44) | PRPS1LMNASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL17103045 | 0.78 | MAPT (0.43) | PRPS1LMNARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393574-B1 | Hexitol derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5053408-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0393574-A2 | Hexitol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |