Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040948 | 0.92 | L3MBTL1 (0.55) | SMN1; SMN2NPSR1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9044249 | 0.91 | PTGDR2 (0.59) | SMN1; SMN2NPSR1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9040258 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9041639 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2NPSR1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8391300 | 0.85 | PPARG (0.69) | ALDH1A1PPARGAGTR1AGTR2 | |
| SCHEMBL9042383 | 0.85 | PPARG (0.60) | LMNAL3MBTL1PPARGAGTR1AGTR2 | |
| SCHEMBL9041375 | 0.84 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL9040689 | 0.84 | TNF (0.59) | PPARGDRD2TBXA2RAGTR1AGTR2 | |
| SCHEMBL9041947 | 0.84 | PPARG (0.51) | SMN1; SMN2ALDH1A1LMNAL3MBTL1PPARG | |
| SCHEMBL9040403 | 0.83 | PPARG (0.50) | SMN1; SMN2ALDH1A1LMNAL3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |