SCHEMBL904060

SCHEMBL904060

CC(C)(C)OC(=O)NCCCCl

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.65
MEN1 O00255 1/20 0.61
GAA P10253 1/20 0.61
KMT2A Q03164 1/20 0.61
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
CA1 P00915 8/20 0.53
CA2 P00918 8/20 0.53
CA12 O43570 7/20 0.53
CA9 Q16790 7/20 0.53
STK17B O94768 1/20 0.50
STK17A Q9UEE5 1/20 0.50
EPHX1 P07099 1/20 0.45
HTT P42858 1/20 0.44
DRD2 P14416 2/20 0.43
FAAH O00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959096 0.94 TDP1 (0.68) TDP1MEN1GAAKMT2AMAOA
SCHEMBL28636908 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1486465 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL28630680 0.92 TDP1 (0.71) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1531287 0.88 TDP1 (0.58) TDP1MEN1GAAKMT2AMAOA
SCHEMBL569251 0.87 TDP1 (0.74) TDP1MEN1GAAKMT2AMAOA
SCHEMBL3020258 0.87 TDP1 (0.81) TDP1MEN1GAAKMT2AMAOA
SCHEMBL25756212 0.86 TDP1 (0.54) TDP1MEN1GAAKMT2AMAOA
SCHEMBL25770346 0.86 TDP1 (0.58) TDP1MEN1GAAKMT2AMAOA
SCHEMBL3025184 0.85 TDP1 (0.85) TDP1MEN1GAAKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775227-A Roxatidine intermediate Synthesis process of intermediate 3 浙江华纳药业有限公司 2025-04-08 CN claimed
CN-119080663-A Efficient low-cost synthesis method of azetidine hydrochloride 南宁师范大学 2024-12-06 CN claimed
US-20260115187-A1 TRICYCLIC SKELETON COMPOUND AND USE THEREOF IN PREPARATION OF ANTITUMOR DRUG ZHONGSHAN HOSPITAL, FUDAN UNIVERSITY (CN) 2026-04-30 US disclosed
US-20260078099-A1 COMPOUND, PREPARATION METHOD THEREOF, AND LIPID NANOPARTICLE AND PHARMACEUTICAL COMPOSITION SUZHOU HEALIRNA BIOTECHNOLOGY CO., LTD. (CN) 2026-03-19 US disclosed
EP-4705278-A1 ANTIMICROBIAL CONJUGATED OLIGOELECTROLYTES AS BROAD-SPECTRUM ANTIBIOTICS The Regents of University of California (US) 2026-03-11 EP disclosed
EP-4650349-A1 COMPOUND, PREPARATION METHOD, AND LIPID NANOPARTICLES AND PHARMACEUTICAL COMPOSITION THEREOF Suzhou Healirna Biotechnology Co., Ltd. (CN) 2025-11-19 EP disclosed
CN-119775227-A Roxatidine intermediate Synthesis process of intermediate 3 浙江华纳药业有限公司 2025-04-08 CN disclosed
US-20250066335-A1 POLYSUBSTITUTED 4-HYDROXYPYRIDINE AND 4-HYDROXYQUINOLINE DERIVATIVES AS GPR84 ANTAGONISTS UNIVERSITY OF COPENHAGEN (DK) 2025-02-27 US disclosed
EP-4486453-A1 BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS F. Hoffmann-La Roche AG (CH) 2025-01-08 EP disclosed
CN-119080663-A Efficient low-cost synthesis method of azetidine hydrochloride 南宁师范大学 2024-12-06 CN disclosed
CN-119080663-A Efficient low-cost synthesis method of azetidine hydrochloride 南宁师范大学 2024-12-06 CN disclosed
WO-1999018073-A1 AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1999-04-15 WO disclosed
US-5773465-A Tartronic acids, their acetalic ethers and o-esters DOMPE FARMACEUTICI S.P.A. (IT) 1998-06-30 US disclosed
US-5656656-A Tartronic acids, their acetalic ethers and O-esters DOMPE FARMACEUTICI S.P.A. (IT) 1997-08-12 US disclosed
EP-0667850-B1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE FARMACEUTICI SPA (IT) 1997-05-28 EP disclosed
EP-0667850-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. DOMPE FARMACEUTICI SPA (IT) 1995-08-23 EP disclosed
WO-1994010127-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE' FARMACEUTICI S.P.A. (IT) 1994-05-11 WO disclosed
EP-0254080-B1 MALONIC ACID DERIVATIVES AND METHODS FOR THEIR SYNTHESIS ENIRICERCHE S.p.A. (IT) 1993-03-17 EP disclosed
US-4914226-A Malonic acid derivatives and methods for their synthesis ENIRICERCHE S.P.A. (IT) 1990-04-03 US disclosed
EP-0254080-A2 Malonic acid derivatives and methods for their synthesis ENIRICERCHE S.p.A. (IT) 1988-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078099-A1 COMPOUND, PREPARATION METHOD THEREOF, AND LIPID NANOPARTICLE AND PHARMACEUTICAL COMPOSITION SGMS1, LDLR, NR5A1 TDP1 1929/4885MEN1 317/4885GAA 3827/4885
US-20260115187-A1 TRICYCLIC SKELETON COMPOUND AND USE THEREOF IN PREPARATION OF ANTITUMOR DRUG HCCS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MCL1 TDP1 4399/4885MEN1 903/4885GAA 4268/4885
US-20250066335-A1 POLYSUBSTITUTED 4-HYDROXYPYRIDINE AND 4-HYDROXYQUINOLINE DERIVATIVES AS GPR84 ANTAGONISTS GPR84, GPR88, GPR65 TDP1 3144/4885MEN1 4705/4885GAA 1453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.