Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9882815 | 0.79 | ALDH1A1 (0.53) | ALDH1A1P2RX4PDE4APDE4BPDE4C | |
| SCHEMBL9043723 | 0.78 | ALDH1A1 (0.51) | ALDH1A1P2RX4PDE4APDE4BPDE4C | |
| SCHEMBL9041922 | 0.78 | ALDH1A1 (0.51) | ALDH1A1P2RX4PDE4APDE4BPDE4C | |
| SCHEMBL9042252 | 0.75 | ALDH1A1 (0.49) | ALDH1A1P2RX4PDE4APDE4BPDE4C | |
| SCHEMBL9042446 | 0.75 | ALDH1A1 (0.49) | ALDH1A1P2RX4KAT2BPDE4APDE4B | |
| SCHEMBL7305503 | 0.74 | ALDH1A1 (0.47) | ALDH1A1P2RX4PDE4APDE4BPDE4C | |
| SCHEMBL7299091 | 0.74 | TSHR (0.56) | ALDH1A1P2RX4MAPTHSD17B10POLB | |
| SCHEMBL15833034 | 0.73 | ALDH1A1 (0.44) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6090368 | 0.71 | GLS (0.66) | ALDH1A1MAPTHSD17B10SLC9A1GLS | |
| SCHEMBL9042105 | 0.70 | KMT2A (0.43) | ALDH1A1P2RX4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613470-B1 | NOVEL 4-CINNOLINONE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1996-01-10 | — | — | EP | claimed |