Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042446 | 0.81 | ALDH1A1 (0.49) | KMT2AALDH1A1HPGDPDE4APDE4B | |
| SCHEMBL9042355 | 0.76 | CNR2 (0.60) | ALDH1A1BCHEACHEPDE4APDE4B | |
| SCHEMBL9882815 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HPGDPDE4APDE4BPDE4C | |
| SCHEMBL9042252 | 0.73 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1BCHEACHE | |
| SCHEMBL9043723 | 0.72 | ALDH1A1 (0.51) | KMT2AALDH1A1HPGDPDE4APDE4B | |
| SCHEMBL9041922 | 0.72 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1HPGDPDE4A | |
| SCHEMBL7299091 | 0.71 | TSHR (0.56) | KMT2AMEN1ALDH1A1HPGDP2RX4 | |
| SCHEMBL9041998 | 0.70 | ALDH1A1 (0.49) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7305503 | 0.69 | ALDH1A1 (0.47) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL958429 | 0.69 | KDM4E (0.57) | KMT2AMEN1ALDH1A1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613470-B1 | NOVEL 4-CINNOLINONE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1996-01-10 | — | — | EP | claimed |