Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.60 |
| ▸ | CNR1 | P21554 | 5/20 | 0.60 |
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042252 | 0.81 | ALDH1A1 (0.49) | CNR2CNR1ACHESLC6A4KDM4E | |
| SCHEMBL9042105 | 0.76 | KMT2A (0.43) | ACHEKDM4EBCHEALDH1A1PDE4A | |
| SCHEMBL9882815 | 0.73 | ALDH1A1 (0.53) | KDM4EALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL9041922 | 0.72 | ALDH1A1 (0.51) | KDM4EALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL9043723 | 0.72 | ALDH1A1 (0.51) | KDM4EALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL7299091 | 0.71 | TSHR (0.56) | CNR2KDM4ECYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL9042446 | 0.70 | ALDH1A1 (0.49) | CNR2KDM4EHTR2CALDH1A1PDE4A | |
| SCHEMBL9041998 | 0.70 | ALDH1A1 (0.49) | SLC6A4KDM4ESLC6A2ALDH1A1POLB | |
| SCHEMBL24014642 | 0.69 | CNR1 (0.46) | CNR2CNR1ACHESLC6A4KDM4E | |
| SCHEMBL12092607 | 0.69 | CNR2 (0.76) | CNR2CNR1ACHESLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613470-B1 | NOVEL 4-CINNOLINONE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1996-01-10 | — | — | EP | claimed |