Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10037548 | 0.84 | NPC1 (0.39) | LMNAKDM4ENPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28802116 | 0.78 | ALDH1A1 (0.34) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL901600 | 0.75 | TNNC1 (0.47) | LMNAKDM4EALDH1A1 | |
| Biphenyl SCHEMBL27676192 | 0.74 | CRHBP (0.44) | GSRLMNANPC1ALDH1A1RAB9A | |
| Nitric Acid SCHEMBL9803283 | 0.73 | GSR (0.53) | GSRLMNAMEN1KMT2AHTR1A | |
| SCHEMBL27794151 | 0.72 | LMNA (0.39) | GSRLMNAALDH1A1 | |
| Aniline SCHEMBL27543715 | 0.72 | TSHR (0.42) | GSRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL9636037 | 0.71 | GSR (0.44) | GSRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL5521085 | 0.71 | ALDH1A1 (0.67) | GSRLMNAMEN1KMT2AKDM4E | |
| SCHEMBL1348353 | 0.71 | ALDH1A1 (0.67) | GSRLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041359-A1 | PROCESS FOR MAKING FINGOLIMOD | SYNTHON B.V. (NL) | 2012-04-05 | — | — | WO | disclosed |