Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056076 | 0.80 | MAPT (0.50) | GAAALDH1A1POLBHPGDCYP1A2 | |
| SCHEMBL9054959 | 0.72 | MAPT (0.42) | GAAALDH1A1POLBHPGDCYP1A2 | |
| SCHEMBL19953563 | 0.70 | ALDH1A1 (0.46) | ALDH1A1POLBHPGDCYP1A2MEN1 | |
| SCHEMBL9734334 | 0.69 | NPC1 (0.42) | ALDH1A1POLBHPGDMEN1KMT2A | |
| SCHEMBL9043612 | 0.66 | POLB (0.46) | ALDH1A1POLBHPGDCYP2D6KMT2A | |
| SCHEMBL9028941 | 0.66 | KDM4E (0.40) | GAAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL916737 | 0.65 | ALDH1A1 (0.53) | ALDH1A1POLBHPGDMEN1KMT2A | |
| SCHEMBL28850201 | 0.65 | ALDH1A1 (0.53) | ALDH1A1POLBHPGDMEN1KMT2A | |
| SCHEMBL9533603 | 0.63 | MEN1 (0.44) | ALDH1A1POLBHPGDMEN1KMT2A | |
| SCHEMBL17554507 | 0.62 | EDNRB (0.43) | ALDH1A1POLBHPGDEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553130-B1 | PYRROLIDINE DIONE DERIVATIVES | PFIZER (US) | 1996-01-03 | — | — | EP | claimed |