Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043598 | 0.81 | ALDH1A1 (0.55) | SMN1; SMN2HSD17B10ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9042485 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2HSD17B10ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9045382 | 0.79 | KDM4E (0.39) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL9042445 | 0.77 | LMNA (0.42) | SMN1; SMN2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9042389 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL9043948 | 0.76 | KMT2A (0.47) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL9041633 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL9042235 | 0.73 | L3MBTL1 (0.60) | SMN1; SMN2HSD17B10ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9053052 | 0.68 | L3MBTL1 (0.39) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL6612380 | 0.65 | L3MBTL1 (0.67) | SMN1; SMN2HSD17B10ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553130-B1 | PYRROLIDINE DIONE DERIVATIVES | PFIZER (US) | 1996-01-03 | — | — | EP | claimed |