Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056076 | 0.81 | MAPT (0.50) | L3MBTL1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL9054959 | 0.73 | MAPT (0.42) | L3MBTL1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL29229610 | 0.72 | POLB (0.47) | L3MBTL1POLBALDH1A1KDM4ECYP1A2 | |
| SCHEMBL9042425 | 0.70 | GAA (0.41) | POLBALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL9042389 | 0.69 | ALDH1A1 (0.47) | L3MBTL1POLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9043948 | 0.68 | KMT2A (0.47) | POLBALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9042485 | 0.68 | ALDH1A1 (0.46) | L3MBTL1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL9043162 | 0.68 | SMN1; SMN2 (0.48) | L3MBTL1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL9042445 | 0.67 | LMNA (0.42) | L3MBTL1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3004854 | 0.65 | ALDH1A1 (0.43) | L3MBTL1POLBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553130-B1 | PYRROLIDINE DIONE DERIVATIVES | PFIZER (US) | 1996-01-03 | — | — | EP | claimed |